Funny how a friend mentioned that to me, and this new mobo has a button on the outside to just click and it does that. However, I figured out the problem. Since I accidently reformatted my windows 10 USB key, I had to make a new one. It appeared to work but the install kept failing. I tried something different, which was in the notes on the guide I was using. Since I didn't have my old windows PC available I had to use my work macbook, but macs don't natively allow you to format a USB to boot windows. Had to do some command line stuff, simple enough except it didnt work the first many times and it worked now because I changed the partitioning from GPT to MBR and the install kicked off. I then added all my drives back in after it completed. Now everything is working. Audio works as expected too (initial issue). I'm so happy to have this fixed, and yet so annoyed I lost literally 6 hours of my day troubleshooting this.
Anyway, as to my storage set up (it's complex, and was not a reason for my issues)
1x 500G M.2 NVMe, this is my OS drive
2x 1.6TB PCIe NVMe, I don't seem to be able to RAID0 these, so I created a spanned volume so both of these look like one big drive to Widows. This is where I will install all games and applications. NOTHING, but the OS will get installed on the C (M.2) drive.
1x 3TB SATA, this is for my old historical data. This is full and I will migrate this data too...
2x 4TB SATA, one is from my old PC and is about 2/3 full of video storage. I added a second one, I will migrate the data off the 3TB onto this 4TB and remove the 3TB drive.
2x 2TB SSD drives, one is from my old PC and is full storing all my video game footage and active video edits. I added a second and will use this for extended active video storage
so that's 5/6 of my SATA ports on the mobo, the 6th goes to my blu-ray drive, and once I decom that 3TB drive, Ill use the open SATA port to connect my SATA connector on my chassis which allows me to pop an external bare hard drive right into it.