But it does!! And yes, I am going to go into it, because this is fascinating and important to me
So like, okay. PlayStation controllers. Level analog sticks. The left thumb has to reach over to an (to me) unnatural position to move the thumbstick which eventually leads to cramping and discomfort in the thumb. On the Xbox and Switch pro controllers, your thumbs fall on the left analog stick and the right face buttons naturally. For my hands it's a natural fit, an ergonomic design. Further, the thumbsticks are convex on the PlayStation controllers which drives me insane. The concave design of the Xbox thumbstick allows for a much better grip which leads to more precise movement and aiming. Then the D-pad and second analog stick are below each thumb, where you're likely going to use them less than the stick and face buttons on the top of the controller.
Now people do find the PS controller comfy and that's totally okay, but for me, those are the biggest reasons why the sticks being out of alignment makes perfect sense to me. That's partially why the GameCube controller was the best controller ever made imo for the longest time; the face buttons were uniquely designed to be distinct so you know what each individual button feels like, and the analog stick was staggered from the C stick for ergonomic purposes.
I'm on my third cup of coffee, sorry.