Huh. Huh.
I lived on 2nd Street for three years (2nd and Christian) and on Broad street just south of City Hall for two years, and my experience is EXACTLY the opposite. There are, of course, dicks everywhere, but I would wear my Giants shirt on Sunday, and despite some ribbing and teasing, never faced anything serious or malicious.
Granted, the Schuykill is a traffic nightmare, but now that I am in CT, I have more people I keep in touch with from Philly than in all the other cities I've lived in combined. I have far more disdain for those that come over the river from Jersey than I do the Philly people.