I'm 49, and it seems like I hit the f*****g wall.
This year, I had my first kidney stone (like most of you, I poo-poo'ed it too - "it can't be THAT bad" - until I found myself at 3:00 in the morning, lying on the bathroom floor on my side with a cold tile on my cheek, one bathmat under my torso, a thin strip of cold tile on my lower side, then more bathmat under my hips and thighs, and just moaning in agony and saying to myself "I'll never do this again... wait, what the f*** did I even DO?" Thank god it passed shortly after.
I have the heartburn, but since I quit coffee cold turkey about a month and a half ago, it has pretty much gone by the wayside. An occasional Prilosec (I've take ONE since the coffee left) takes care of bidness.
I too have to lose about 15 pounds. After quitting the coffee, believe it or not I dumped about 10 pounds in about three weeks (no Pop tarts or other carbs in the morning with the coffee is my guess, because I didn't do anything else!)
But not to be too personal here, the BIGGEST pain in the ass is - literally - the dreaded hemorrhoid. I've had them before, apparently mild, and short, but it seems like it's been a constant friend dropping by (again literally) for a visit every couple weeks or so. I had a colonoscopy about a year or so ago, but I'm going to try to get to my doctor (who's a male) this month and have a look see. I've hesitated, because the last time I had the "finger" it was there, but it was one of his PA's, and she was really cute (in a Cote de Pablo/Gal Gadot kind of way) and I was EXTREMELY self-conscious about that. Sorry, TMI - Too Much Ick.