The tricky part of figuring out a lower prilosec dose is the tendency towards a rebound. When I got to one every 3 days I started feeling pretty crappy and went back to two, but I can't say for sure that it wasn't just a temporary rebound.
And I'll check with my docs about H2 blockers. I think that's what they initially put me on after the transplant but after I called an bitched that it wasn't working they said to give prilosec a shot. However, at that point I was taking 6x the amount of prednisone. Now that I'm on a relatively small maintenance dose the H2 blocker might work better for me. I've never been all that comfortable taking the omeprazole long term.
Just curious, what's your maintenance anti rejection regimen. Cyclosporine? Tacrolimus?, Mycophenolate?, azathioprine?
The only reason I ask, is that PPI's can decrease your Tacrolimus level. Not that you can't take a PPI, its just that consistency is usually encouraged. That's one thing to consider if you are in fact on Tac.
And that's just a good rule in general for all men reading this thread. H2 blockers like zantac or PPI's like prilosec can effect absorption of other medications, so its usually encouraged to separate them from taking of other drugs by 2 hours.
PPI's really shouldn't be used chronically, despite that fact that a majority of people are, unfortunately. If people are experiencing acid reflux AKA heart burn, then a change of diet is encouraged (or moderation at the very least) and also its recommended not to lie down for at least 45 mins after eating. I am guilty of that one, but staying upright after eating a heartburn inducing meal will help.